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The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases
CHAPTER SUMMARY: Interleukin-15 (IL-15) is a 14-15-kDa member of the 4α helix bundle family of cytokines that stimulate T and NK (natural killer) cells. IL-15 and IL-2 utilize heterotrimeric receptors that include the cytokine-specific private receptors IL-2Rα and IL-15Rα, as well as two receptor el...
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| Format: | Artigo |
| Language: | Inglês |
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BioMed Central
2002
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240159/ https://ncbi.nlm.nih.gov/pubmed/12110135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar584 |
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