Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition

BACKGROUND: The quantification of experimentally-induced alterations in biological pathways remains a major challenge in systems biology. One example of this is the quantitative characterization of alterations in defined, established metabolic pathways from complex metabolomic data. At present, the...

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Main Authors: Xiao, Xiaolin, Dawson, Neil, MacIntyre, Lynsey, Morris, Brian J, Pratt, Judith A, Watson, David G, Higham, Desmond J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239845/
https://ncbi.nlm.nih.gov/pubmed/21575198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-72
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