Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts

INTRODUCTION: Innate defence regulator (IDR) peptides are synthetic cationic peptides, variants of naturally occurring innate immune effector molecules known as host defence peptides. IDR peptides were recently demonstrated to limit infection-associated inflammation selectively without compromising...

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Main Authors: Turner-Brannen, Emily, Choi, Ka-Yee, Lippert, Dustin ND, Cortens, John P, Hancock, Robert EW, El-Gabalawy, Hani, Mookherjee, Neeloffer
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239371/
https://ncbi.nlm.nih.gov/pubmed/21835002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3440
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