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Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy

Blocking IL-1 in patients with knee osteoarthritis is an attractive strategy. Cohen and colleagues report a randomised, placebo-controlled, multiple-dose trial using a monoclonal antibody blocking IL-1 type 1 receptor. They failed to show any positive results in terms of evolution of pain for up to...

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Détails bibliographiques
Auteurs principaux: Chevalier, Xavier, Conrozier, Thierry, Richette, Pascal
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239369/
https://ncbi.nlm.nih.gov/pubmed/21888686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3436
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