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A new weapon against an old target
High expression of folate receptors is characteristic for the effector cell population of synovial macrophages in synovial inflammation. A new drug conjugate, EC0746, targets the folate inhibitor aminopterin to folate receptors. In vitro studies show that this conjugate acts antiproliferatively and...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3239345/ https://ncbi.nlm.nih.gov/pubmed/21861856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3392 |
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