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Giant cell arteritis: immune and vascular aging as disease risk factors

Susceptibility for giant cell arteritis increases with chronological age, in parallel with age-related restructuring of the immune system and age-induced remodeling of the vascular wall. Immunosenescence results in shrinkage of the naïve T-cell pool, contraction of T-cell diversity, and impairment o...

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Autors principals: Mohan, Shalini V, Liao, Y Joyce, Kim, Jonathan W, Goronzy, Jörg J, Weyand, Cornelia M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239337/
https://ncbi.nlm.nih.gov/pubmed/21861860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3358
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