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Combined molecular dynamics and continuum solvent studies of the pre-pore Cry4Aa trimer suggest its stability in solution and how it may form pore

Cry4Aa toxin is one of the highly specific mosquito-larvicidal proteins produced by the bacterium Bacillus thuringiensis subspecies israelensis. It is thought to form pores in the larval midgut membrane that cause membrane leakage and subsequent insect death. Therefore, Cry4Aa and other Cry toxins h...

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Detalhes bibliográficos
Main Authors: Taveecharoenkool, Taveechai, Angsuthanasombat, Chanan, Kanchanawarin, Chalermpol
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239330/
https://ncbi.nlm.nih.gov/pubmed/20465833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-5036-3-10
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