Identification of an unique CXCR4 epitope whose ligation inhibits infection by both CXCR4 and CCR5 tropic human immunodeficiency type-I viruses

BACKGROUND: Small chemical compounds which target chemokine receptors have been developed against human immunodeficiency virus type 1 (HIV-1) and are under investigation for use as anti-HIV-1 microbicides. In addition, monoclonal antibodies (mAbs) against chemokine receptors have also been shown to...

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Hlavní autoři: Adachi, Tetsuya, Tanaka, Reiko, Kodama, Akira, Saito, Mineki, Takahashi, Yoshiaki, Ansari, Aftab A, Tanaka, Yuetsu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239297/
https://ncbi.nlm.nih.gov/pubmed/22018245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-84
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