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Novel dimeric structure of phage ϕ29-encoded protein p56: insights into uracil-DNA glycosylase inhibition

Protein p56 encoded by the Bacillus subtilis phage ϕ29 inhibits the host uracil-DNA glycosylase (UDG) activity. To get insights into the structural basis for this inhibition, the NMR solution structure of p56 has been determined. The inhibitor defines a novel dimeric fold, stabilized by a combinatio...

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Detalhes bibliográficos
Main Authors: Asensio, Juan Luis, Pérez-Lago, Laura, Lázaro, José M., González, Carlos, Serrano-Heras, Gemma, Salas, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239192/
https://ncbi.nlm.nih.gov/pubmed/21890898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr667
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