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tRNA anticodon replacement experiments show that ribosomal frameshifting can be caused by doublet decoding.

The expression of certain normal genes requires a specific ribosomal frameshift event because the mRNA has the coding information for one protein in two different reading frames. One of several possible mechanisms for this involves recognition of a nontriplet codon by a noncognate tRNA. The AGUC-dec...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bruce, A G, Atkins, J F, Gesteland, R F
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2425361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5062
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