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Oxaliplatin-Induced Neuropathy in Colorectal Cancer

Oxaliplatin use in palliative and adjuvant treatment of colon cancer is frequently limited by cumulative neurotoxicity, leading to reduced quality of life and decreased dose. The mechanism of this neurotoxicity is unclear, but may relate to neuronal voltage-gated sodium channels involving calcium ch...

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Detalhes bibliográficos
Main Authors: Weickhardt, Andrew, Wells, Keith, Messersmith, Wells
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238400/
https://ncbi.nlm.nih.gov/pubmed/22203844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/201593
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