Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer

Alternative splicing of the IgIII loop of fibroblast growth factor receptors (FGFRs) 1–3 produces b- and c-variants of the receptors with distinctly different biological impact based on their distinct ligand-binding spectrum. Tissue-specific expression of these splice variants regulates interactions...

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Detalhes bibliográficos
Main Authors: Holzmann, Klaus, Grunt, Thomas, Heinzle, Christine, Sampl, Sandra, Steinhoff, Heinrich, Reichmann, Nicole, Kleiter, Miriam, Hauck, Marlene, Marian, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238399/
https://ncbi.nlm.nih.gov/pubmed/22203889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/950508
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