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Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential
The endoplasmic reticulum (ER) plays a crucial role in protein folding, assembly, and secretion. Disruption of ER homeostasis may lead to accumulation of misfolded or unfolded proteins in the ER lumen, a condition referred to as ER stress. In response to ER stress, a signal transduction pathway know...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3238353/ https://ncbi.nlm.nih.gov/pubmed/22195283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/841362 |
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