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Lowering extracellular Na+ concentration releases autocrine growth factors from renal epithelial cells.

Sodium influx is an important early signal during the onset of mitogenesis in many types of cells. From this observation, one would predict that a decrease in extracellular Na+ concentration might retard cell proliferation. We tested this prediction by exposing sets of cultures of monkey kidney epit...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Walsh-Reitz, M M, Gluck, S L, Waack, S, Toback, F G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3460070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.13.4764
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