Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort

BACKGROUND: The hepatitis C virus (HCV) infects nearly 3% of the World's population, causing severe liver disease in many. Standard of care therapy is currently pegylated interferon alpha and ribavirin (PegIFN/R), which is effective in less than half of those infected with the most common viral...

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Hlavní autoři: Smith, Katherine R, Suppiah, Vijayaprakash, O'Connor, Kate, Berg, Thomas, Weltman, Martin, Abate, Maria Lorena, Spengler, Ulrich, Bassendine, Margaret, Matthews, Gail, Irving, William L, Powell, Elizabeth, Riordan, Stephen, Ahlenstiel, Golo, Stewart, Graeme J, Bahlo, Melanie, George, Jacob, Booth, David R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238183/
https://ncbi.nlm.nih.gov/pubmed/21884576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm273
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