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Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

Human recombinant tumor necrosis factor (rTNF) was found to act directly on cultured human vascular endothelium to induce a tissue factor-like procoagulant activity (PCA). After a 4-hr incubation in rTNF (100 units/ml), serially passaged endothelial cells isolated from umbilical veins, saphenous vei...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bevilacqua, M P, Pober, J S, Majeau, G R, Fiers, W, Cotran, R S, Gimbrone, M A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3487091/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4533
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