Gipr Is Essential for Adrenocortical Steroidogenesis; However, Corticosterone Deficiency Does Not Mediate the Favorable Metabolic Phenotype of Gipr(−/−) Mice

Glucose-dependent insulinotropic polypeptide (GIP) promotes glucose-dependent insulin secretion. However, GIP also enhances glucocorticoid secretion and promotes adiposity. Because obesity and diabetes are glucocorticoid dependent, we examined whether the effects of GIP on energy balance and glycemi...

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Autors principals: Bates, Holly E., Campbell, Jonathan E., Ussher, John R., Baggio, Laurie L., Maida, Adriano, Seino, Yutaka, Drucker, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237652/
https://ncbi.nlm.nih.gov/pubmed/22043004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1060
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