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A Mechanistic Investigation into the Zinc Carbenoid-Mediated Homologation Reaction by DFT Methods: Is a Classical Donor–Acceptor Cyclopropane Intermediate Involved?

[Image: see text] An extensive density functional theory (DFT, M05-2X) investigation has been performed on the zinc carbenoid-mediated homologation reaction of β-keto esters. The mechanistic existence of a classical donor–acceptor cyclopropane intermediate was probed to test the traditional school o...

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Detalhes bibliográficos
Main Authors: Eger, Wilhelm A., Zercher, Charles K., Williams, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237639/
https://ncbi.nlm.nih.gov/pubmed/20879758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo101590t
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