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LPA Is a Chemorepellent for B16 Melanoma Cells: Action through the cAMP-Elevating LPA(5) Receptor

Lysophosphatidic acid (LPA), a lipid mediator enriched in serum, stimulates cell migration, proliferation and other functions in many cell types. LPA acts on six known G protein-coupled receptors, termed LPA(1–6), showing both overlapping and distinct signaling properties. Here we show that, unexpec...

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Autors principals: Jongsma, Maikel, Matas-Rico, Elisa, Rzadkowski, Adrian, Jalink, Kees, Moolenaar, Wouter H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237609/
https://ncbi.nlm.nih.gov/pubmed/22195035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029260
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