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Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells.
Cross-linking the membrane immunoglobulins of resting B cells leads to activation as judged by increased inositol phospholipid metabolism, intracellular free calcium concentration ([Ca2+]i), and cell volume. Such activated B cells enter S phase in the presence of B-cell stimulatory factor 1. Phorbol...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
1986
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3086884/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4474 |
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