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Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells.

Cross-linking the membrane immunoglobulins of resting B cells leads to activation as judged by increased inositol phospholipid metabolism, intracellular free calcium concentration ([Ca2+]i), and cell volume. Such activated B cells enter S phase in the presence of B-cell stimulatory factor 1. Phorbol...

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Bibliografiske detaljer
Main Authors: Mizuguchi, J, Beaven, M A, Li, J H, Paul, W E
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC323756/
https://ncbi.nlm.nih.gov/pubmed/3086884
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