Interaction between CRHR1 and BDNF Genes Increases the Risk of Recurrent Major Depressive Disorder in Chinese Population

BACKGROUND: An important etiological hypothesis about depression is stress has neurotoxic effects that damage the hippocampal cells. Corticotropin-releasing hormone (CRH) regulates brain-derived neurotrophic factor (BDNF) expression through influencing cAMP and Ca2+ signaling pathways during the cou...

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Detalhes bibliográficos
Main Authors: Xiao, Zheman, Liu, Wanhong, Gao, Kai, Wan, Qirong, Yang, Can, Wang, Huiling, Wang, Xiaoping, Wang, Gaohua, Liu, Zhongchun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237493/
https://ncbi.nlm.nih.gov/pubmed/22194899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028733
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