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Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiae

The de novo biosynthetic machinery for both sphingolipid and ergosterol production in yeast is localized in the endoplasmic reticulum (ER) and Golgi. The interconnections between the two pathways are still poorly understood, but they may be connected in specialized membrane domains, and specific kno...

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Main Authors: Alvarez-Vasquez, Fernando, Riezman, Howard, Hannun, Yusuf A., Voit, Eberhard O.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237449/
https://ncbi.nlm.nih.gov/pubmed/22194828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028344
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