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Tetraspanin CD81 is required for the αvβ5-integrin-dependent particle-binding step of RPE phagocytosis

Retinal pigment epithelial (RPE) cells are among the most active phagocytes in the body. Every morning, circadian shedding of outer segment fragments by photoreceptor cells activates a synchronized phagocytic response by RPE cells that is critical for vision. RPE cells require αvβ5 integrin receptor...

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Bibliographic Details
Main Authors: Chang, Yongen, Finnemann, Silvia C.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237194/
https://ncbi.nlm.nih.gov/pubmed/17684062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.006361
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