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Primary lack of efficacy of infliximab therapy for rheumatoid arthritis: pharmacokinetic characterization and assessment of switching to tocilizumab

To characterize primary failure to infliximab and determine the efficacy of switching to tocilizumab in patients with rheumatoid arthritis (RA), we examined 24 RA patients who had started on infliximab therapy (3 mg/kg) as their first biological agent. Nine of the 24 patients were found to be primar...

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Detalhes bibliográficos
Main Authors: Mori, Shunsuke, Ueki, Yukitaka
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236821/
https://ncbi.nlm.nih.gov/pubmed/21533855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10165-011-0460-5
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