Characterization of human prorenin expressed in mammalian cells from cloned cDNA.

Human preprorenin was synthesized in Chinese hamster ovary (CHO) cells transfected with an expression vector containing renin cDNA sequences. These cells secrete an inactive form of renin (EC 3.4.23.15) that can be activated by trypsin. This inactive renin is precipitable by antibody generated again...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fritz, L C, Arfsten, A E, Dzau, V J, Atlas, S A, Baxter, J D, Fiddes, J C, Shine, J, Cofer, C L, Kushner, P, Ponte, P A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323681/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3520565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4114
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