Cigarette Smoking and p16(INK4α) Gene Promoter Hypermethylation in Non-Small Cell Lung Carcinoma Patients: A Meta-Analysis

BACKGROUND: Aberrant methylation of promoter DNA and transcriptional repression of specific tumor suppressor genes play an important role in carcinogenesis. Recently, many studies have investigated the association between cigarette smoking and p16(INK4α) gene hypermethylation in lung cancer, but cou...

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Autores principales: Zhang, Bo, Zhu, Wei, Yang, Ping, Liu, Tao, Jiang, Mei, He, Zhi-Ni, Zhang, Shi-Xin, Chen, Wei-Qing, Chen, Wen
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236763/
https://ncbi.nlm.nih.gov/pubmed/22174919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028882
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