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Inhibition of EGF-induced ERK/MAP kinase-mediated astrocyte proliferation by µ opioids: integration of G protein and β-arrestin 2-dependent pathways

Although µ, κ, and δ opioids activate extracellular signal-regulated kinase (ERK)/mitogen-activated protein (MAP) kinase, the mechanisms involved in their signaling pathways and the cellular responses that ensue differ. Here we focused on the mechanisms by which µ opioids rapidly (min) activate ERK...

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Detalhes bibliográficos
Main Authors: Miyatake, Mayumi, Rubinstein, Tal J., McLennan, Gregory P., Belcheva, Mariana M., Coscia, Carmine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236703/
https://ncbi.nlm.nih.gov/pubmed/19457093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06156.x
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