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Mapping second messenger systems in the brain: differential localizations of adenylate cyclase and protein kinase C.

[3H]Forskolin and [3H]phorbol 12,13-dibutyrate have been used to map the adenylate cyclase and phosphatidylinositol systems respectively in brain slices by light-microscopic autoradiography. [3H]Forskolin binding to brain sections is displaced potently by forskolin (KD approximately equal to 15 nM)...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Worley, P F, Baraban, J M, De Souza, E B, Snyder, S H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323664/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3012547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.4053
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