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Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

The relationship of the neurofibrillary tangle, found in Alzheimer disease and aged brains, to normal or abnormal cytoskeletal proteins remains elusive. Although immunohistochemical studies have yielded disparate results, most antigenic determinants localized to neurofibrillary tangles are cytoskele...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Wood, J G, Mirra, S S, Pollock, N J, Binder, L I
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2424015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.4040
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