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Herpes simplex virus immediate early infected-cell polypeptide 4 binds to DNA and promotes transcription.

In herpes simplex virus (HSV)-infected cells, there is a sequential expression of viral genes. In vivo experiments have implicated the Mr 175,000 immediate early protein ICP4 (infected-cell polypeptide 4) in the regulation of viral RNA synthesis, but the mechanism whereby ICP4 regulates transcriptio...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Beard, P, Faber, S, Wilcox, K W, Pizer, L I
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3012542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.4016
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