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Tregs and infections: on the potential value of modifying their function

CD4(+) T cells, which express a master transcription factor, Foxp3, have been recognized as bona fide Tregs. These cells are essential to maintain immune homeostasis in healthy as well as infected mice and humans. Extensive investigations in the last decade have provided ways to manipulate the Foxp3...

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Autori principali: Sehrawat, Sharvan, Rouse, Barry T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236550/
https://ncbi.nlm.nih.gov/pubmed/21914856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0611271
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