Heterotypic piRNA Ping-Pong Requires Qin, a Protein with Both E3 ligase and Tudor Domains

piRNAs guide PIWI proteins to silence transposons in animal germ cells. Reciprocal cycles of piRNA-directed RNA cleavage—catalyzed by the PIWI proteins Aubergine (Aub) and Argonaute3 (Ago3) in Drosophila melanogaster—expand the population of antisense piRNAs in response to transposon expression, a p...

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Autores principales: Zhang, Zhao, Xu, Jia, Koppetsch, Birgit S., Wang, Jie, Tipping, Cindy, Ma, Shengmei, Weng, Zhiping, Theurkauf, William E., Zamore, Phillip D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236501/
https://ncbi.nlm.nih.gov/pubmed/22099305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.10.011
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