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Cotransfer of the Ed alpha and Ad beta genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule.

Ia molecules play a key role in antigen recognition by T lymphocytes. To analyze the structural features of the individual alpha and beta chains relevant to the assembly of intact Ia molecules, mouse fibroblasts were cotransfected with various combinations of haplotype- and isotype-mismatched Ia alp...

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Dettagli Bibliografici
Autori principali: Malissen, B, Shastri, N, Pierres, M, Hood, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC323644/
https://ncbi.nlm.nih.gov/pubmed/3086873
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