An Off-Target Nucleostemin RNAi Inhibits Growth in Human Glioblastoma-Derived Cancer Stem Cells

Glioblastomas (GBM) may contain a variable proportion of active cancer stem cells (CSCs) capable of self-renewal, of aggregating into CD133(+) neurospheres, and to develop intracranial tumors that phenocopy the original ones. We hypothesized that nucleostemin may contribute to cancer stem cell biolo...

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Detalhes bibliográficos
Main Authors: Gil-Ranedo, Jon, Mendiburu-Eliçabe, Marina, García-Villanueva, Mercedes, Medina, Diego, del Álamo, Marta, Izquierdo, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236221/
https://ncbi.nlm.nih.gov/pubmed/22174890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028753
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