The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation

Arrestins are multifunctional signaling adaptors originally discovered as proteins that “arrest” G protein activation by G protein-coupled receptors (GPCRs). Recently GPCR complexes with arrestins have been proposed to activate G protein-independent signaling pathways. In particular, arrestin-depend...

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Main Authors: Coffa, Sergio, Breitman, Maya, Hanson, Susan M., Callaway, Kari, Kook, Seunghyi, Dalby, Kevin N., Gurevich, Vsevolod V.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236217/
https://ncbi.nlm.nih.gov/pubmed/22174878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028723
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