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A yeast mutant lacking mitochondrial manganese-superoxide dismutase is hypersensitive to oxygen.
The nuclear gene for manganese-containing superoxide dismutase (MnSOD; superoxide:superoxide oxidoreductase, EC 1.15.1.1) of yeast mitochondria was mapped on chromosome VIII and inactivated by gene disruption. The resulting mutant lacked any protein cross-reacting with anti-MnSOD antibodies, and its...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1986
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323615/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3520557/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3820 |
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