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Linkage between ligand binding and the dimer-tetramer equilibrium in the Monod-Wyman-Changeux model of hemoglobin.

G. Weber [(1984) Proc. Natl. Acad. Sci. USA 81, 7098-7102] has inferred that the Monod-Wyman-Changeux (MWC) model for ligand binding by hemoglobin would require (contrary to experimental evidence) that increased ligand binding must promote stabilization of alpha 2 beta 2 tetramers with respect to di...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Edelstein, S J, Edsall, J T
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1986
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323610/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3459157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3796
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