Interactions of Interleukin-8 with the Human Chemokine Receptor CXCR1 in Phospholipid Bilayers by NMR Spectroscopy

CXCR1 is a receptor for the chemokine interleukin-8 (IL-8), a mediator of immune and inflammatory responses. Strategically located in the cell membrane, CXCR1 binds to IL-8 with high affinity, and subsequently transduces a signal across the membrane bilayer to a G-protein activated second messenger...

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Hlavní autoři: Park, Sang Ho, Casagrande, Fabio, Cho, Leah, Albrecht, Lauren, Opella, Stanley J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236022/
https://ncbi.nlm.nih.gov/pubmed/22019593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.08.025
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