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Direct Entry to Erythronlolides via a Cyclic Bis[Allene]
The complexity and low tractability of antibiotic macrolides pose serious challenges to addressing the problem of resistance through semi- or total synthesis. Here we describe a new strategy, the preparation of a complex, yet tractable, macrocycle, and the transformation of this macrocycle into a ra...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235949/ https://ncbi.nlm.nih.gov/pubmed/21894913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja207496p |
| Clibeanna: |
Cuir Clib Leis
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