Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

Estrogens regulate body weight and reproduction primarily through actions on estrogen receptor-α (ERα). However, ERα-expressing cells mediating these effects are not identified. We demonstrate that brain-specific deletion of ERα in female mice causes abdominal obesity stemming from both hyperphagia...

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Autors principals: Xu, Yong, Nedungadi, Thekkethil P., Zhu, Liangru, Sobhani, Nasim, Irani, Boman G., Davis, Kathryn E., Zhang, Xiaorui, Zou, Fang, Gent, Lana M., Hahner, Lisa D., Khan, Sohaib A., Elias, Carol F., Elmquist, Joel K., Clegg, Deborah J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235745/
https://ncbi.nlm.nih.gov/pubmed/21982706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.08.009
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