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A Two-Stage Estimation Method for Random Coefficient Differential Equation Models with Application to Longitudinal HIV Dynamic Data

We propose a two-stage estimation method for random coefficient ordinary differential equation (ODE) models. A maximum pseudo-likelihood estimator (MPLE) is derived based on a mixed-effects modeling approach and its asymptotic properties for population parameters are established. The proposed method...

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Detalhes bibliográficos
Main Authors: Fang, Yun, Wu, Hulin, Zhu, Li-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235714/
https://ncbi.nlm.nih.gov/pubmed/22171150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5705/ss.2009.156
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