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Pharmacological Chaperones for Misfolded Gonadotropin-Releasing Hormone Receptors

Structural alterations provoked by mutations or genetic variations in the gene sequence of G protein-coupled receptors may lead to abnormal function of the receptor molecule and, ultimately, to disease. While some mutations lead to changes in domains involved in agonist binding, receptor activation...

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Bibliografiske detaljer
Main Authors: Conn, P. Michael, Ulloa-Aguirre, Alfredo
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235646/
https://ncbi.nlm.nih.gov/pubmed/21907908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-385952-5.00008-7
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