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Structure of the food-poisoning Clostridium perfringens enterotoxin reveals similarity to the aerolysin-like pore-forming toxins

Clostridium perfringens enterotoxin (CPE) is a major cause of food poisoning and antibiotic-associated diarrhoea. Upon its release from C. perfringens spores, CPE binds to its receptor, claudin, at the tight junctions between the epithelial cells of the gut wall, and subsequently forms pores in the...

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Detalhes bibliográficos
Main Authors: Briggs, David C., Naylor, Claire E., Smedley, James G., Lukoyanova, Natalya, Robertson, Susan, Moss, David S., McClane, Bruce A., Basak, Ajit K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235586/
https://ncbi.nlm.nih.gov/pubmed/21839091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.066
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