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Inhibition Of Notch Activity Promotes Nonmitotic Regeneration of Hair Cells in the Adult Mouse Utricles

The capacity of adult mammals to regenerate sensory hair cells is not well defined. To explore early steps in this process, we examined reactivation of a transiently expressed developmental gene, Atoh1, in adult mouse utricles after neomycin-induced hair cell death in culture. Using an adenoviral re...

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Autores principales: Lin, Vincent, Golub, Justin S., Nguyen, Tot Bui, Hume, Clifford R., Oesterle, Elizabeth C., Stone, Jennifer S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235543/
https://ncbi.nlm.nih.gov/pubmed/22031879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2057-11.2011
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