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GLUTAREDOXIN 2 (GRX2) KNOCKOUT INCREASES SENSITIVITY TO OXIDATIVE STRESS IN MOUSE LENS EPITHELIAL CELLS

Glutaredoxin belongs to the oxidoreductase family with cytosolic glutaredoxin 1 (Grx1) and mitochondrial gluraredoxin 2 (Grx2) isoforms. Of the two isozymes, the function of Grx2 is not well understood. This paper studied the effect of Grx2 deletion on cellular function using primary lens epithelial...

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Detalhes bibliográficos
Main Authors: Wu, HongLi, Lin, LiRen, Giblin, Frank, Ho, Ye-Sheh, Lou, Marjorie F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235406/
https://ncbi.nlm.nih.gov/pubmed/21983434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.09.011
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