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Effect of Emergence of Fluoroquinolone Resistance on Intrinsic Expression of P-Glycoprotein Phenotype in Corneal Epithelial Cells

PURPOSE: Multidrug resistance (MDR) represents a major obstacle to the success of antimicrobial fluoroquinolone (FQ) therapy. MDR-associated efflux protein pumps antimicrobial agents out of the corneal cells, leading to suboptimal eradication of microbes. This article examines whether long-term FQ (...

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Detalhes bibliográficos
Main Authors: Barot, Megha, Gokulgandhi, Mitan R., Haghnegahdar, Megan, Dalvi, Pranjali, Mitra, Ashim K.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235346/
https://ncbi.nlm.nih.gov/pubmed/21830912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2011.0076
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