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Protease and cyclooxygenase inhibitors synergistically prevent activation of human platelets.

Thrombin induces platelet aggregation and formation of a fibrin clot in platelet-rich plasma; leupeptin, a protease inhibitor, partially inhibits platelet aggregation, but it does not inhibit fibrin clot formation. Indomethacin does not inhibit either thrombin-induced platelet aggregation or fibrin...

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Detalhes bibliográficos
Main Authors: Ruggiero, M, Lapetina, E G
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC323534/
https://ncbi.nlm.nih.gov/pubmed/3458190
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