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Localization of antimicrobial peptides on polymerized liposomes leading to their enhanced efficacy against Pseudomonas aeruginosa()

Antimicrobial peptide IG-25 (a truncated version of LL-37 of the cathelicidin family) tethering an azido-capped poly(ethylene glycol) chain at the N-terminus was site-specifically attached to alkynyl-terminated polymerized liposomes using copper catalyzed “click” reaction, leading to an 18 fold enha...

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Detalhes bibliográficos
Main Authors: Kumar, Amit, Kolar, Satya S., Zao, Meriong, McDermott, Alison M., Cai, Chengzhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235330/
https://ncbi.nlm.nih.gov/pubmed/21229178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00207k
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