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Serum Analysis of Tryptophan Catabolism Pathway: Correlation with Crohn’s Disease Activity

BACKGROUND: Indoleamine 2,3 dioxygenase 1 (IDO1) is a tryptophan catabolizing enzyme with immunotolerance promoting functions. We sought to determine if increased gut expression of IDO1 in Crohn’s disease (CD) would result in detectable changes in serum levels of tryptophan and the initial IDO1 path...

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Detalhes bibliográficos
Main Authors: Gupta, Nitin K, Thaker, Ameet I, Kanuri, Navya, Riehl, Terrence E, Rowley, Christopher W, Stenson, William F, Ciorba, Matthew A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235239/
https://ncbi.nlm.nih.gov/pubmed/21823214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21849
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