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Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector

Direct cellular reprogramming is a powerful new tool for regenerative medicine. In efforts to understand and treat Parkinson's Disease (PD), which is marked by the degeneration of dopaminergic neurons in the midbrain, direct reprogramming provides a valuable new source of these cells. Astrocyte...

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書誌詳細
主要な著者: Addis, Russell C., Hsu, Fu-Chun, Wright, Rebecca L., Dichter, Marc A., Coulter, Douglas A., Gearhart, John D.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235158/
https://ncbi.nlm.nih.gov/pubmed/22174877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028719
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